Singing accent research is underexplored compared to speech accent studies, primarily due to the scarcity of suitable datasets. Existing singing datasets often suffer from detail loss, frequently resulting from the vocal-instrumental separation process. Additionally, they often lack regional accent annotations. To address this, we introduce the Multi-Accent Mandarin Dry-Vocal Singing Dataset (MADVSD). MADVSD comprises over 670 hours of dry vocal recordings from 4,206 native Mandarin speakers across nine distinct Chinese regions. In addition to each participant recording audio of three popular songs in their native accent, they also recorded phonetic exercises covering all Mandarin vowels and a full octave range. We validated MADVSD through benchmark experiments in singing accent recognition, demonstrating its utility for evaluating state-of-the-art speech models in singing contexts. Furthermore, we explored dialectal influences on singing accent and analyzed the role of vowels in accentual variations, leveraging MADVSD's unique phonetic exercises.

Diffusion models have emerged as a leading framework in generative modeling, poised to transform the traditionally slow and costly process of drug discovery. This review provides a systematic comparison of their application in designing two principal therapeutic modalities: small molecules and therapeutic peptides. We dissect how the unified framework of iterative denoising is adapted to the distinct molecular representations, chemical spaces, and design objectives of each modality. For small molecules, these models excel at structure-based design, generating novel, pocket-fitting ligands with desired physicochemical properties, yet face the critical hurdle of ensuring chemical synthesizability. Conversely, for therapeutic peptides, the focus shifts to generating functional sequences and designing de novo structures, where the primary challenges are achieving biological stability against proteolysis, ensuring proper folding, and minimizing immunogenicity. Despite these distinct challenges, both domains face shared hurdles: the scarcity of high-quality experimental data, the reliance on inaccurate scoring functions for validation, and the crucial need for experimental validation. We conclude that the full potential of diffusion models will be unlocked by bridging these modality-specific gaps and integrating them into automated, closed-loop Design-Build-Test-Learn (DBTL) platforms, thereby shifting the paradigm from mere chemical exploration to the on-demand engineering of novel~therapeutics.

Image manipulation localization (IML) faces a fundamental trade-off between minimizing annotation cost and achieving fine-grained localization accuracy. Existing fully-supervised IML methods depend heavily on dense pixel-level mask annotations, which limits scalability to large datasets or real-world deployment. In contrast, the majority of existing weakly-supervised IML approaches are based on image-level labels, which greatly reduce annotation effort but typically lack precise spatial localization. To address this dilemma, we propose BoxPromptIML, a novel weakly-supervised IML framework that effectively balances annotation cost and localization performance. Specifically, we propose a coarse region annotation strategy, which can generate relatively accurate manipulation masks at lower cost. To improve model efficiency and facilitate deployment, we further design an efficient lightweight student model, which learns to perform fine-grained localization through knowledge distillation from a fixed teacher model based on the Segment Anything Model (SAM). Moreover, inspired by the human subconscious memory mechanism, our feature fusion module employs a dual-guidance strategy that actively contextualizes recalled prototypical patterns with real-time observational cues derived from the input. Instead of passive feature extraction, this strategy enables a dynamic process of knowledge recollection, where long-term memory is adapted to the specific context of the current image, significantly enhancing localization accuracy and robustness. Extensive experiments across both in-distribution and out-of-distribution datasets show that Box-PromptIML outperforms or rivals fully-supervised models, while maintaining strong generalization, low annotation cost, and efficient deployment characteristics.

By automating knowledge discovery, boosting hypothesis creation, integrating transdisciplinary insights, and enabling coope ration within innovation ecosystems, LLMs dramatically improve the efficiency and effectiveness of research processes. Through extensive analysis of scientific literature, patent databases, and experimental data, these models enable more flexible and infor med R&D workflows, ultimately accelerating innovation cycles and lowering time - to - market for breakthrough ideas.

China waged a campaign of harassment and intimidation directed at a UK university to get it to shut down sensitive research into alleged human rights abuses, documents seen by the BBC show. Sheffield Hallam University staff in China were threatened by individuals described by them as being from China's National Security Service who demanded the research being done in Sheffield be halted. And access to the university's websites from China was blocked, impeding its ability to recruit Chinese students, in a campaign of threats and intimidation lasting more than two years. In an internal email from July 2024, university officials said attempting to retain the business in China and publication of the research are now untenable bedfellows. When the UK government learned of the case, the then Foreign Secretary David Lammy issued a warning to his Chinese counterpart that it would not tolerate attempts to suppress academic freedoms at UK universities, the BBC understands.

Precipitation prediction has undergone a profound transformation -- from early symbolic and empirical methods rooted in divination and observation, to modern technologies based on atmospheric physics and artificial intelligence. This review traces the historical and technological evolution of precipitation forecasting, presenting a survey about end-to-end precipitation prediction technologies that spans ancient practices, the foundations of meteorological science, the rise of numerical weather prediction (NWP), and the emergence of machine learning (ML) and deep learning (DL) models. We first explore traditional and indigenous forecasting methods, then describe the development of physical modeling and statistical frameworks that underpin contemporary operational forecasting. Particular emphasis is placed on recent advances in neural network-based approaches, including automated deep learning, interpretability-driven design, and hybrid physical-data models. By compositing research across multiple eras and paradigms, this review not only depicts the history of end-to-end precipitation prediction but also outlines future directions in next generation forecasting systems.

Video Anomaly Detection (VAD) aims to identify and locate deviations from normal patterns in video sequences. Traditional methods often struggle with substantial computational demands and a reliance on extensive labeled datasets, thereby restricting their practical applicability. To address these constraints, we propose HiProbe-VAD, a novel framework that leverages pre-trained Multimodal Large Language Models (MLLMs) for VAD without requiring fine-tuning. In this paper, we discover that the intermediate hidden states of MLLMs contain information-rich representations, exhibiting higher sensitivity and linear separability for anomalies compared to the output layer. To capitalize on this, we propose a Dynamic Layer Saliency Probing (DLSP) mechanism that intelligently identifies and extracts the most informative hidden states from the optimal intermediate layer during the MLLMs reasoning. Then a lightweight anomaly scorer and temporal localization module efficiently detects anomalies using these extracted hidden states and finally generate explanations. Experiments on the UCF-Crime and XD-Violence datasets demonstrate that HiProbe-VAD outperforms existing training-free and most traditional approaches. Furthermore, our framework exhibits remarkable cross-model generalization capabilities in different MLLMs without any tuning, unlocking the potential of pre-trained MLLMs for video anomaly detection and paving the way for more practical and scalable solutions.

Retrieval-Augmented Generation (RAG) addresses large language model (LLM) hallucinations by grounding responses in external knowledge, but its effectiveness is compromised by poor-quality retrieved contexts containing irrelevant or noisy information. While existing approaches attempt to improve performance through context selection based on predefined context quality assessment metrics, they show limited gains over standard RAG. We attribute this limitation to their failure in holistically utilizing available information (query, context list, and generator) for comprehensive quality assessment. Inspired by recent advances in data selection, we reconceptualize context quality assessment as an inference-time data valuation problem and introduce the Contextual Influence Value (CI value). This novel metric quantifies context quality by measuring the performance degradation when removing each context from the list, effectively integrating query-aware relevance, list-aware uniqueness, and generator-aware alignment. Moreover, CI value eliminates complex selection hyperparameter tuning by simply retaining contexts with positive CI values. To address practical challenges of label dependency and computational overhead, we develop a parameterized surrogate model for CI value prediction during inference. The model employs a hierarchical architecture that captures both local query-context relevance and global inter-context interactions, trained through oracle CI value supervision and end-to-end generator feedback. Extensive experiments across 8 NLP tasks and multiple LLMs demonstrate that our context selection method significantly outperforms state-of-the-art baselines, effectively filtering poor-quality contexts while preserving critical information. Code is available at https://github.com/SJTU-DMTai/RAG-CSM.

The generation of high-quality, diverse, and prompt-aligned images is a central goal in image-generating diffusion models. The popular classifier-free guidance (CFG) approach improves quality and alignment at the cost of reduced variation, creating an inherent entanglement of these effects. Recent work has successfully disentangled these properties by guiding a model with a separately trained, inferior counterpart; however, this solution introduces the considerable overhead of requiring an auxiliary model. We challenge this prerequisite by introducing In-situ Autoguidance, a method that elicits guidance from the model itself without any auxiliary components. Our approach dynamically generates an inferior prediction on the fly using a stochastic forward pass, reframing guidance as a form of inference-time self-correction. We demonstrate that this zero-cost approach is not only viable but also establishes a powerful new baseline for cost-efficient guidance, proving that the benefits of self-guidance can be achieved without external models.

With the global population increasing and arable land resources becoming increasingly limited, smart and precision agriculture have emerged as essential directions for sustainable agricultural development. Artificial intelligence (AI), particularly deep learning models, has been widely adopted in applications such as crop monitoring, pest detection, and yield prediction. Among recent generative models, diffusion models have demonstrated considerable potential in agricultural image processing, data augmentation, and remote sensing analysis. Compared to traditional generative adversarial networks (GANs), diffusion models exhibit greater training stability and superior image generation quality, effectively addressing challenges such as limited annotated datasets and imbalanced sample distributions in agricultural scenarios. This paper reviews recent advancements in the application of diffusion models within agriculture, focusing on their roles in crop disease and pest detection, remote sensing image enhancement, crop growth prediction, and agricultural resource management. Diffusion models have been found useful in improving tasks like image generation, denoising, and data augmentation in agriculture, especially when environmental noise or variability is present. While their high computational requirements and limited generalizability across domains remain concerns, the approach is gradually proving effective in real-world applications such as precision crop monitoring. As research progresses, these models may help support sustainable agriculture and address emerging challenges in food systems.